Publications

Quantitative and multiplexed microRNA sensing in living cells based on peptide nucleic acid and nano graphene oxide (PANGO)
S.-R. Ryoo, J. Lee, J. Yeo, H.-K. Na, Y.-K. Kim, H. Jang, J. H. Lee, S. W. Han, Y. Lee, V. N. Kim, and D.-H. Min
ACS Nano (2013), 7(7):5882-5891

Development of multiplexed immuno-N-terminomics to reveal the landscape of proteolytic processing in early embryogenesis of Drosophila melanogaster
S. Shin, J. H. Hong, Y. Na, M. Lee, W.-J. Qian, V. N. Kim, and J.-S. Kim^{✉︎ (corresponding author)}
Analytical Chemistry (2020), 92(7):4926-4934

MS1-level proteome quantification platform allowing maximally increased multiplexity for SILAC and in vitro chemical labeling
Y. Choi¹, K. Jeong¹, S. Shin¹, J. W. Lee¹, Y. Lee, S. Kim, S. A. Kim, J. Jung, K. P. Kim, V. N. Kim^{✉︎ (corresponding author)}, and J. S. Kim^{✉︎ (corresponding author)}
Analytical Chemistry (2020), 92(7):4980-4989

miRseqViewer: multi-panel visualization of sequence, structure and expression for analysis of microRNA sequencing data
I. Jang¹, H. Chang¹, Y. Jun, S. Park, J. O. Yang, B. Lee, W. Kim, V. N. Kim, and S. Lee
Bioinformatics (2015), 31(4):596-598

MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL-mediated leukemogenesis
J. Choi, Y.-K. Kim, K. Park, J. Nah, S. S. Yoon, D. W. Kim, V. N. Kim, and R. H. Seong
Blood (2016), 128(17):2117-2129

Gastric carcinogenesis in the miR-222/221 transgenic mouse model
B. Choi¹, J. Yu¹, T.-S. Han, Y.-K. Kim, K. Hur, B.-C. Kang, W. H. Kim, D.-Y. Kim, H.-J. Lee, V. N. Kim, and H.-K. Yang^{✉︎ (corresponding author)}
Cancer Research and Treatment (2016), 49(1):150-160

Functional atlas of vertebrate viral RNA elements that stabilize RNA and enhance translation
J. J. Seo¹, C. Lee¹, D. Lim, M. Jeong, S.-J. Jung, and V. N. Kim^{✉︎ (corresponding author)}
Cell (2026), 189(22):7105-7120.e12

Small and long non-coding RNAs: past, present, and future
L.-L. Chen^{✉︎ (corresponding author)} and V. N. Kim^{✉︎ (corresponding author)}
Cell (2024), 187(23):6451-6485

Functional viromic screens uncover regulatory RNA elements
J. J. Seo¹, S.-J. Jung¹, J. Yang, D.-E. Choi, and V. N. Kim^{✉︎ (corresponding author)}
Cell (2023), 186(15):3291-3306.e21

The architecture of SARS-CoV-2 transcriptome
D. Kim, J.-Y. Lee, J.-S. Yang, J. W. Kim, V. N. Kim^{✉︎ (corresponding author)}, and H. Chang^{✉︎ (corresponding author)}
Cell (2020), 181(4):914-921.e10

Structure of human DROSHA
S. C. Kwon¹, T. A. Nguyen¹, Y.-G. Choi¹, M. H. Jo, S. Hohng, V. N. Kim^{✉︎ (corresponding author)}, and J.-S. Woo^{✉︎ (corresponding author)}
Cell (2016), 164(1-2):81-90

Functional anatomy of the human Microprocessor
T. A. Nguyen, M. H. Jo, Y.-G. Choi, J. Park, S. C. Kwon, S. Hohng, V. N. Kim^{✉︎ (corresponding author)}, and J.-S. Woo^{✉︎ (corresponding author)}
Cell (2015), 161(6):1374-1387

Uridylation by TUT4 and TUT7 marks mRNA for degradation
J. Lim¹, M. Ha¹, H. Chang¹, S. C. Kwon, D. K. Simanshu, D. J. Patel, and V. N. Kim^{✉︎ (corresponding author)}
Cell (2014), 159(6):1365-1376

Emerging roles of RNA modifications: m6A and U-tail
M. Lee, B. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Cell (2014), 158(5):980-987

LIN28A is a suppressor of ER-associated translation in embryonic stem cells
J. Cho¹, H. Chang¹, S. C. Kwon, B. Kim, Y. Kim, J. Choe, M. Ha, Y. K. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Cell (2012), 151(4):765-777

Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs
I. Heo¹, M. Ha¹, J. Lim, M.-J. Yoon, J.-E. Park, S. C. Kwon, H. Chang, and V. N. Kim
Cell (2012), 151(3):521-532

Modifications of small RNAs and their associated proteins
Y.-K. Kim, I. Heo, and V. N. Kim
Cell (2010), 143(5):703-709

Conserved microRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K
S. Hyun¹, J. H. Lee¹, H. Jin¹, J. Nam, B. Namkoong, Gina Lee, J. Chung, and V. N. Kim
Cell (2009), 139(6):1096-1108

Regulating the regulators: posttranslational modifications of RNA silencing factors
I. Heo and V. N. Kim
Cell (2009), 139(1):28-31

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
I. Heo¹, C. Joo¹, Y.-K. Kim¹, M. Ha, M.-J. Yoon, J. Cho, K.-H. Yeom, J. Han, and V. N. Kim
Cell (2009), 138(4):696-708

Posttranscriptional crossregulation between Drosha and DGCR8
J. Han, J. S. Pedersen, S. C. Kwon, C. D. Belair, Y.-K. Kim, K. H. Yeom, W. Y. Yang, D. Haussler, R. Blelloch, and V. N. Kim^{✉︎ (corresponding author)}
Cell (2009), 136(1):75-84

Sorting out small RNAs
V. N. Kim^{✉︎ (corresponding author)}
Cell (2008), 133(1):25-26

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
J. Han¹, Y. Lee¹, K. H. Yeom¹, J. W. Nam, I. Heo, J. K. Rhee, S. Y. Sohn, Y. Cho, B. T. Zhang, and V. N. Kim
Cell (2006), 125(5):887-901

Temporal landscape of microRNA-mediated host-virus crosstalk during productive human cytomegalovirus infection
S. Kim¹, D. Seo¹, D. Kim, Y. Hong, H. Chang, D. Baek, V. N. Kim, S. Lee, and K. Ahn^{✉︎ (corresponding author)}
Cell Host & Microbe (2015), 17(6):838-851

PARN and TOE1 constitute a 3′ end maturation module for nuclear non-coding RNAs
A. Son¹, J.-E. Park¹, and V. N. Kim^{✉︎ (corresponding author)}
Cell Reports (2018), 23(3):888-898

Deletion of human tarbp2 reveals cellular microRNA targets and cell cycle function of TRBP
Y. Kim¹, J. Yeo¹, J. H. Lee¹, J. Cho, D. Seo, J. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Cell Reports (2014), 9(3):1061-1074

The drifting biochemical basis of an essential molecular interaction
Y. Park^{✉︎ (corresponding author)} and V. N. Kim^{✉︎ (corresponding author)}
Cell Systems (2026)

Human embryonic stem cells express a unique set of microRNAs
M. R. Suh, Y. Lee, J. Y. Kim, S. K. Kim, S. H. Moon, J. Y. Lee, K. Y. Cha, H. M. Chung, H. S. Yoon, S. Y. Moon, V. N. Kim^{✉︎ (corresponding author)}, and K. S. Kim^{✉︎ (corresponding author)}
Developmental Biology (2004), 270(2):488-498

Coordinate regulation of the senescent state by selective autophagy
Y. Lee¹, J. Kim¹, M. Kim¹, Y. Kwon, S. Shin, H. Yi, H. Kim, M. Chang, C. Chang, S. Kang, V. N. Kim, J. Kim, J. Kim, S. J. Elledge, and C. Kang^{✉︎ (corresponding author)}
Developmental Cell (2021), 56(10):1512-1525.e7

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis
H. Kim^{1✉︎ (corresponding author)}, Y. Lee¹, S.-M. Kim, S. Jang, H. Choi, J.-W. Lee, T.-D. Kim^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
Developmental Cell (2021), 56(8):1118-1130.e6

MeCP2 caught moonlighting as a suppressor of microRNA processing
J.-S. Woo and V. N. Kim^{✉︎ (corresponding author)}
Developmental Cell (2014), 28(5):477-478

TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms
B. Kim¹, M. Ha¹, L. Loeff¹, H. Chang, D. K. Simanshu, S. Li, M. Fareh, D. J. Patel, C. Joo^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
EMBO Journal (2015), 34(13):1801-1815 Supplementary data

Processing of intronic microRNAs
Y.-K. Kim and V. N. Kim^{✉︎ (corresponding author)}
EMBO Journal (2007), 26(3):775-783

The role of PACT in the RNA silencing pathway
Y. Lee¹, I. Hur¹, S. Y. Park¹, Y.-K. Kim, M. R. Suh, and V. N. Kim^{✉︎ (corresponding author)}
EMBO Journal (2006), 25(3):522-532

MicroRNA genes are transcribed by RNA polymerase II
Y. Lee, M. Kim, J. Han, K. H. Yeom, S. Lee, S. H. Baek, and V. N. Kim^{✉︎ (corresponding author)}
EMBO Journal (2004), 23(20):4051-4060

MicroRNA maturation: stepwise processing and subcellular localization
Y. Lee, K. Jeon, J. T. Lee, S. Kim, and V. N. Kim^{✉︎ (corresponding author)}
EMBO Journal (2002), 21(17):4663-4670

Single-molecule approach to immunoprecipitated protein complexes: insights into miRNA uridylation
K.-H. Yeom, I. Heo, J. Lee, S. Hohng, V. N. Kim^{✉︎ (corresponding author)}, and C. Joo^{✉︎ (corresponding author)}
EMBO Reports (2011), 12(7):690-696

Development of a laboratory-safe and low-cost detection protocol for SARS-CoV-2 of the coronavirus disease 2019 (COVID-19)
J. Won, S. Lee, M. Park, T. Y. Kim, M. G. Park, B. Y. Choi, D. Kim, H. Chang, V. N. Kim, and C. Justin Lee^{✉︎ (corresponding author)}
Experimental Neurobiology (2020), 29(2):107-119

microRNA-30a arbitrates intestinal-type early gastric carcinogenesis by directly targeting ITGA2
J. Min, T. S. Han, Y. Sohn, T. Shimizu, B. Choi, S. W. Bae, K. Hur, S. H. Kong, Y. S. Suh, H. J. Lee, J. S. Kim, J. K. Min, W. H. Kim, V. N. Kim, E. Choi^{✉︎ (corresponding author)}, J. R. Goldenring^{✉︎ (corresponding author)}, and H. K. Yang^{✉︎ (corresponding author)}
Gastric Cancer (2020), 23(4):600-613

Role of the proline-rich disordered domain of DROSHA in intronic microRNA processing
S. Son¹, B. Kim¹, J. Yang, and V. N. Kim^{✉︎ (corresponding author)}
Genes & Development (2023), 37(9-10):383-397

mTAIL-seq reveals dynamic poly(A) tail regulation in oocyte-to-embryo development
J. Lim¹, M. Lee¹, A. Son, H. Chang, and V. N. Kim^{✉︎ (corresponding author)}
Genes & Development (2016), 30(14):1671-1682

Role of the small subunit processome in the maintenance of pluripotent stem cells
K. T. You, J. Park, and V. N. Kim^{✉︎ (corresponding author)}
Genes & Development (2015), 29(19):2004-2009

PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator
Y. Kim, J. H. Lee, J.-E. Park, J. Cho, H. Yi, and V. N. Kim^{✉︎ (corresponding author)}
Genes & Development (2014), 28(12):1310-1322

Conserved microRNA miR-8 controls body size in response to steroid signaling in Drosophila
H. Jin, V. N. Kim^{✉︎ (corresponding author)}, and S. Hyun^{✉︎ (corresponding author)}
Genes & Development (2012), 26(13):1427-1432

Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes
V. N. Kim^{✉︎ (corresponding author)}
Genes & Development (2006), 20(15):1993-1997

The Drosha-DGCR8 complex in primary microRNA processing
J. Han¹, Y. Lee¹, K. H. Yeom, Y.-K. Kim, H. Jin, and V. N. Kim^{✉︎ (corresponding author)}
Genes & Development (2004), 18(24):3016-3027

Downregulation of GFAP, TSP-1, and p53 in human glioblastoma cell line, U373MG, by IE1 protein from human cytomegalovirus
K. Lee, K. Jeon, J. M. Kim, V. N. Kim, D. H. Choi, S. U. Kim, and S. Kim
Glia (2005), 51(1):1-12

MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1
T.-S. Han, K. Hur, G. Xu, B. Choi, Y. Okugawa, Y. Toiyama, H. Oshima, M. Oshima, H.-J. Lee, V. N. Kim, A. N. Chang, A. Goel^{✉︎ (corresponding author)}, and H.-K. Yang^{✉︎ (corresponding author)}
Gut (2015), 64(2):203-214

Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy
J. K. Kim, J. Cho, S. H. Kim, H. C. Kang, D. S. Kim, V. N. Kim, and J. H. Lee^{✉︎ (corresponding author)}
Journal of Clinical Investigation (2019), 129(10):4207-4223

miR-30a-5p as a tumor suppressor gene in gastric cancer
J. Min, T.-S. Han, B. Choi, K. Hur, K. Yanagihara, V. N. Kim^{✉︎ (corresponding author)}, H.-J. Lee^{✉︎ (corresponding author)}, and H.-K. Yang^{✉︎ (corresponding author)}
Journal of Clinical Oncology (2018), 36(4_suppl):84

Analyzing viral epitranscriptomes using nanopore direct RNA sequencing
A. Hong¹, D. Kim¹, V. N. Kim, and H. Chang^{✉︎ (corresponding author)}
Journal of Microbiology (2022), 60(9):867-876

Regulation of ApC/EBP mRNA by the Aplysia AU-rich element-binding protein, ApELAV, and its effects on 5-hydroxytryptamine-induced long-term facilitation
S. J. Yim¹, Y. S. Lee¹, J. A. Lee, D. J. Chang, J. H. Han, H. Kim, H. Park, H. Jun, V. N. Kim, and B. K. Kaang
Journal of Neurochemistry (2006), 98(2):420-429

Deuterium-free, three-plexed peptide diethylation for highly accurate quantitative proteomics
J. Jung, K. Jeong, Y. Choi, S. A. Kim, H. Kim, J. W. Lee, V. N. Kim, K. P. Kim, and J. S. Kim
Journal of Proteome Research (2019), 18(3):1078-1087

fCLIP-seq for transcriptomic footprinting of dsRNA-binding proteins: lessons from DROSHA
B. Kim and V. N. Kim^{✉︎ (corresponding author)}
Methods (2018), 152:3-11

Human UPF1 participates in small RNA-induced mRNA downregulation
H. Jin¹, M. R. Suh¹, J. Han, K.-H. Yeom, Y. Lee, I. Heo, M. Ha, S. Hyun, and V. N. Kim^{✉︎ (corresponding author)}
Molecular and Cellular Biology (2009), 29(21):5789-5799

Time-resolved profiling of RNA binding proteins throughout the mRNA life cycle
Y. Choi¹, B. Um¹, Y. Na, J. Kim, J.-S. Kim^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2024), 84(9):1764-1782.e10

Structural atlas of human primary microRNAs generated by SHAPE-MaP
S. Baek¹, B. Kim¹, H. Jang¹, K. Kim, I. Park, D.-H. Min, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2024), 84(6):1158-1172.e6

A quantitative map of human primary microRNA processing sites
K. Kim¹, S. Baek¹, Y. Lee, C. Bastiaanssen, J. Kim, H. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2021), 81(16):3422-3439.e11

The SARS-CoV-2 RNA interactome
S. Lee¹, Y. Lee¹, Y. Choi, A. Son, Y. Park, K.-M. Lee, J. Kim, J.-S. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2021), 81(13):2838-2850.e6

Genomic clustering facilitates nuclear processing of suboptimal pri-miRNA loci
R. Shang^{1✉︎ (corresponding author)}, S. C. Baek¹, K. Kim, B. Kim, V. N. Kim, and E. C. Lai^{✉︎ (corresponding author)}
Molecular Cell (2020), 78(2):303-316.e4

A mechanism for microRNA arm switching regulated by uridylation
H. Kim¹, J. Kim¹, S. Yu, Y.-Y. Lee, J. Park, R. J. Choi, S.-J. Yoon, S.-G. Kang, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2020), 78(6):1224-1236.e5

Molecular basis for the single-nucleotide precision of primary microRNA processing
S. C. Kwon, S. C. Baek, Y. G. Choi, J. Yang, Y. Lee, J.-S. Woo^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2019), 73(3):505-518.e5

PKR senses nuclear and mitochondrial signals by interacting with endogenous double-stranded RNAs
Y. Kim^{1✉︎ (corresponding author)}, J. Park¹, S. Kim¹, M. Kim, M. G. Kang, C. Kwak, M. Kang, B. Kim, H. W. Rhee, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2018), 71(6):1051-1063.e6

PABP cooperates with the CCR4-NOT complex to promote mRNA deadenylation and block precocious decay
H. Yi¹, J. Park¹, M. Ha, J. Lim, H. Chang, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2018), 70(6):1081-1088.e5

Terminal uridylyltransferases execute programmed clearance of maternal transcriptome in vertebrate embryos
H. Chang¹, J. Yeo¹, J.-g. Kim, H. Kim, J. Lim, M. Lee, H. H. Kim, J. Ohk, H.-Y. Jeon, H. Lee, H. Jung, K.-W. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2018), 70(1):72-82.e7

Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and noncanonical substrates
B. Kim¹, K. Jeong¹, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2017), 66(2):258-269.e5

Regulation of poly(A) tail and translation during the somatic cell cycle
J.-E. Park¹, H. Yi¹, Y. Kim¹, H. Chang, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2016), 62(3):462-471

Adenylation of maternally inherited microRNAs by Wispy
M. Lee, Y. Choi, K. Kim, H. Jin, J. Lim, T. A. Nguyen, J. Yang, M. Jeong, A. J. Giraldez, H. Yang, D. J. Patel, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2014), 56(5):696-707

TAIL-seq: genome-wide determination of poly(A) tail length and 3′ end modifications
H. Chang¹, J. Lim¹, M. Ha, and V. N. Kim^{✉︎ (corresponding author)}
Molecular Cell (2014), 53(6):1044-1052

A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer
Y. Tian¹, D. K. Simanshu¹, J.-B. Ma, J.-E. Park, I. Heo, V. N. Kim, and D. J. Patel^{✉︎ (corresponding author)}
Molecular Cell (2014), 53(4):606-616

Short structured RNAs with low GC content are selectively lost during extraction from a small number of cells
Y.-K. Kim, J. Yeo, B. Kim, M. Ha, and V. N. Kim
Molecular Cell (2012), 46(6):893-895

MicroRNA factory: RISC assembly from precursor microRNAs
Y. Kim and V. N. Kim
Molecular Cell (2012), 46(4):384-386

Lin28 mediates the terminal uridylation of let-7 precursor microRNA
I. Heo¹, C. Joo¹, J. Cho, M. Ha, J. Han, and V. N. Kim
Molecular Cell (2008), 32(2):276-284

Structural and functional insights into Dom34, a key component of no-go mRNA decay
H. H. Lee, Y. S. Kim, K. H. Kim, I. Heo, S. K. Kim, O. Kim, H. K. Kim, J. Y. Yoon, H. S. Kim, D. J. Kim, S. J. Lee, H. J. Yoon, S. J. Kim, B. G. Lee, H. K. Song, V. N. Kim, C. M. Park, and S. W. Suh
Molecular Cell (2007), 27(6):938-950

Control of splicing efficiency by the mouse histone H2a element in a murine leukemia virus-based retroviral vector
J. T. Lee, S. S. Yu, V. N. Kim, and S. Kim
Molecular Therapy (2007), 15(1):167-172

Small RNAs: classification, biogenesis, and function
V. N. Kim^{✉︎ (corresponding author)}
Molecules and Cells (2005), 19(1):1-15

Structural basis for chaperone-guided assembly of RNA-induced silencing complex
Y.-Y. Lee¹, M. Jeong¹, H. Lee¹, D. Lee, J. Lee, J. Park, V. N. Kim^{✉︎ (corresponding author)}, and S.-H. Roh^{✉︎ (corresponding author)}
Nature (2026), 655(8125):1339-1348

Sequence determinant of small RNA production by DICER
Y. Lee¹, H. Kim¹, and V. N. Kim^{✉︎ (corresponding author)}
Nature (2023), 615(7951):323-330

Structure of the human DICER–pre-miRNA complex in a dicing state
Y. Lee¹, H. Lee¹, H. Kim¹, V. N. Kim^{✉︎ (corresponding author)}, and S. H. Roh^{✉︎ (corresponding author)}
Nature (2023), 615(7951):331-338

Dicer recognizes the 5′ end of RNA for efficient and accurate processing
J.-E. Park¹, I. Heo¹, Y. Tian, D. K. Simanshu, H. Chang, D. Jee, D. J. Patel, and V. N. Kim^{✉︎ (corresponding author)}
Nature (2011), 475(7355):201-205

The nuclear RNase III Drosha initiates microRNA processing
Y. Lee, C. Ahn, J. Han, H. Choi, J. Kim, J. Yim, J. Lee, P. Provost, O. Radmark, S. Kim, and V. N. Kim
Nature (2003), 425(6956):415-419

RNA stability enhancers for durable base-modified mRNA therapeutics
S.-J. Jung¹, J. J. Seo¹, S. Lee¹, S.-I. Hyun, J.-e. Lee, S. Lee, Y. Lee, H. Chang, H. Lee, J.-H. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Nature Biotechnology (2026), 44(11):1831-1844

RNA-targeting CRISPR comes of age
V. N. Kim^{✉︎ (corresponding author)}
Nature Biotechnology (2018), 36(1):44-45

Identification of the SARS-CoV-2 genome packaging signal in the nsp12-coding region
Y. Park^{✉︎ (corresponding author)}, J. Lim, H. Cho, A. Son, M. Jeong, Y.-s. Lee^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
Nature Communications (2026), 17(1):8500

ERH promotes primary microRNA processing beyond cluster assistance
H. Jang, J. Park, and V. N. Kim^{✉︎ (corresponding author)}
Nature Communications (2025), 16(1):7913

Innate immune responses against mRNA vaccine promote cellular immunity through IFN-β at the injection site
S. Kim¹, J. H. Jeon¹, M. Kim, Y. Lee, Y.-H. Hwang, M. Park, C. H. Li, T. Lee, J.-A. Lee, Y.-M. Kim, D. Kim, H. Lee, Y.-J. Kim, V. N. Kim, J.-E. Park^{✉︎ (corresponding author)}, and J. Yeo^{✉︎ (corresponding author)}
Nature Communications (2024), 15(1):7226

Photoactivatable ribonucleosides mark base-specific RNA-binding sites
J. W. Bae, S. Kim, V. N. Kim^{✉︎ (corresponding author)}, and J.-S. Kim^{✉︎ (corresponding author)}
Nature Communications (2021), 12(1):6026

The regulatory impact of RNA-binding proteins on microRNA targeting
S. Kim¹, S. Kim¹, H. R. Chang¹, D. Kim¹, J. Park, N. Son, J. Park, M. Yoon, G. Chae, Y.-K. Kim, V. N. Kim, Y. K. Kim, J.-W. Nam, C. Shin^{✉︎ (corresponding author)}, and D. Baek^{✉︎ (corresponding author)}
Nature Communications (2021), 12(1):5057

Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
C. Kim¹, S. Sung¹, J.-S. Kim¹, H. Lee, Y. Jung, S. Shin, E. Kim, J. J. Seo, J. Kim, D. Kim, H. Niida, V. N. Kim, D. Park^{✉︎ (corresponding author)}, and J. Lee^{✉︎ (corresponding author)}
Nature Communications (2021), 12(1):1097

L1 retrotransposons exploit RNA m6A modification as an evolutionary driving force
S. Hwang, H. Jung, S. Mun, S. Lee, K. Park, S. C. Baek, H. Moon, H. Kim, B. Kim, Y. Choi, Y. Go, W. Tang, J. Choi, J. Choi, H. Cha, H. Park, P. Liang, V. N. Kim, K. Han^{✉︎ (corresponding author)}, and K. Ahn^{✉︎ (corresponding author)}
Nature Communications (2021), 12(1):880

Quantification of purified endogenous miRNAs with high sensitivity and specificity
S. Shin¹, Y. Jung¹, H. Uhm, M. Song, S. Son, J. Goo, C. Jeong, J.-J. Song, V. N. Kim, and S. Hohng^{✉︎ (corresponding author)}
Nature Communications (2020), 11(1):6033

Pontin functions as an essential coactivator for Oct4-dependent lincRNA expression in mouse embryonic stem cells
K. Boo¹, J. Bhin¹, Y. Jeon, J. Kim, H. J. Shin, J. E. Park, K. Kim, C. R. Kim, H. Jang, I. H. Kim, V. N. Kim, D. Hwang^{✉︎ (corresponding author)}, H. Lee^{✉︎ (corresponding author)}, and S. H. Baek^{✉︎ (corresponding author)}
Nature Communications (2015), 6(1):6810

Cell cycle micromanagement in embryonic stem cells
V. N. Kim^{✉︎ (corresponding author)}
Nature Genetics (2008), 40(12):1391-1392

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8+ T cell responses by targeting the aminopeptidase ERAP1
S. Kim, S. Lee, J. Shin, Y. Kim, I. Evnouchidou, D. Kim, Y.-K. Kim, Y.-E. Kim, J.-H. Ahn, S. R. Riddell, E. Stratikos, V. N. Kim, and K. Ahn^{✉︎ (corresponding author)}
Nature Immunology (2011), 12(10):984-991

Human cytomegalovirus long non-coding RNA counteracts nuclear cGAS to facilitate immune evasion
S. Lee, S. Kim, H. Kim, D. Lee, D. Jeong, H. Kim, J. Park, K. Park, J. Hur, S. Kim, V. N. Kim, and K. Ahn^{✉︎ (corresponding author)}
Nature Microbiology (2025), 10(9):2275-2290

The biogenesis and regulation of animal microRNAs
H. Kim¹, Y.-Y. Lee¹, and V. N. Kim^{✉︎ (corresponding author)}
Nature Reviews Molecular Cell Biology (2024), 26(4):276-296

A tale of noncanonical tails: gene regulation by post-transcriptional RNA tailing
S. Yu and V. N. Kim^{✉︎ (corresponding author)}
Nature Reviews Molecular Cell Biology (2020), 21(9):542-556

Regulation of microRNA biogenesis
M. Ha and V. N. Kim
Nature Reviews Molecular Cell Biology (2014), 15(8):509-524

Biogenesis of small RNAs in animals
V. N. Kim^{✉︎ (corresponding author)}, J. Han, and M. C. Siomi^{✉︎ (corresponding author)}
Nature Reviews Molecular Cell Biology (2009), 10(2):126-139

MicroRNA biogenesis: coordinated cropping and dicing
V. N. Kim^{✉︎ (corresponding author)}
Nature Reviews Molecular Cell Biology (2005), 6(5):376-385

Deadenylation kinetics of mixed poly(A) tails at single-nucleotide resolution
Y.-S. Lee^{1✉︎ (corresponding author)}, Y. Levdansky¹, Y. Jung, V. N. Kim^{✉︎ (corresponding author)}, and E. Valkov^{✉︎ (corresponding author)}
Nature Structural & Molecular Biology (2024), 31(5):826-834

Short poly(A) tails are protected from deadenylation by the LARP1-PABP complex
J. Park¹, M. Kim¹, H. Yi¹, K. Baeg¹, Y. Choi, Y. Lee, J. Lim, and V. N. Kim^{✉︎ (corresponding author)}
Nature Structural & Molecular Biology (2023), 30(3):330-338

Chemical RNA digestion enables robust RNA-binding site mapping at single amino acid-resolution
J. W. Bae, S. C. Kwon, Y. Na, V. N. Kim^{✉︎ (corresponding author)}, and J. S. Kim^{✉︎ (corresponding author)}
Nature Structural & Molecular Biology (2020), 27(7):678-682

Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing
D. Kim¹, Y. Lee¹, S.-J. Jung¹, J. Yeo¹, J. J. Seo, Y.-Y. Lee, J. Lim, H. Chang, J. Song, J. Yang, J. S. Kim, G. Jung, K. Ahn, and V. N. Kim^{✉︎ (corresponding author)}
Nature Structural & Molecular Biology (2020), 27(6):581-588

U-tail as a guardian against invading RNAs
J. Yeo and V. N. Kim^{✉︎ (corresponding author)}
Nature Structural & Molecular Biology (2018), 25(10):903-905

TALEN-based knockout library for human microRNAs
Y.-K. Kim¹, G. Wee¹, J. Park, J. Kim, D. Baek, J.-S. Kim^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
Nature Structural & Molecular Biology (2013), 20(12):1458-1464

The RNA-binding protein repertoire of embryonic stem cells
S. C. Kwon, H. Yi, K. Eichelbaum, S. Föhr, B. Fischer, K. T. You, A. Castello, J. Krijgsveld, M. W. Hentze, and V. N. Kim
Nature Structural & Molecular Biology (2013), 20(9):1122-1130

miR-29 miRNAs activate p53 by targeting p85a and CDC42
S. Y. Park¹, J. H. Lee¹, M. Ha, J. W. Nam, and V. N. Kim
Nature Structural & Molecular Biology (2009), 16(1):23-29

Crystal structure of human DGCR8 core
S. Y. Sohn¹, W. J. Bae¹, J. J. Kim, K. H. Yeom, V. N. Kim, and Y. Cho
Nature Structural & Molecular Biology (2007), 14(9):847-853

SARS-CoV-2 Nsp2 recruits GIGYF2 near viral replication sites and supports viral protein production
J. Kim¹, Y. Park¹, D. Yoon¹, S. Lee¹, H. Kim¹, K.-Y. Ban, J. Yang, D.-E. Choi, J. Kim, J.-S. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Nucleic Acids Research (2025), 53(14):gkaf674

FAX-RIC enables robust profiling of dynamic RNP complex formation in multicellular organisms in vivo
Y. Na, H. Kim, Y. Choi, S. Shin, J. H. Jung, S. C. Kwon, V. N. Kim^{✉︎ (corresponding author)}, and J. S. Kim^{✉︎ (corresponding author)}
Nucleic Acids Research (2021), 49(5):e28

ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8
S. C. Kwon¹, H. Jang¹, S. Shen¹, S. C. Baek, K. Kim, J. Yang, J. Kim, J.-S. Kim, S. Wang, Y. Shi, F. Li^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
Nucleic Acids Research (2020), 48(19):11097-11112

Bias-minimized quantification of microRNA reveals widespread alternative processing and 3′ end modification
H. Kim¹, J. Kim¹, K. Kim, H. Chang, K. You, and V. N. Kim^{✉︎ (corresponding author)}
Nucleic Acids Research (2019), 47(5):2630-2640

Microprocessor depends on hemin to recognize the apical loop of primary microRNA
T. A. Nguyen^{1✉︎ (corresponding author)}, J. Park¹, T. L. Dang, Y. G. Choi, and V. N. Kim^{✉︎ (corresponding author)}
Nucleic Acids Research (2018), 46(11):5726-5736

miRGator v3.0: a microRNA portal for deep sequencing, expression profiling and mRNA targeting
S. Cho, I. Jang, Y. Jun, S. Yoon, M. Ko, Y. Kwon, I. Choi, H. Chang, D. Ryu, B. Lee, V. N. Kim, W. Kim^{✉︎ (corresponding author)}, and S. Lee^{✉︎ (corresponding author)}
Nucleic Acids Research (2012), 41(D1):D252-D257

The co-regulation mechanism of transcription factors in the human gene regulatory network
J. Kim, M. Choi, J. R. Kim, H. Jin, V. N. Kim, and K. H. Cho^{✉︎ (corresponding author)}
Nucleic Acids Research (2012), 40(18):8849-8861

Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer
Y.-K. Kim, J. Yu, T. S. Han, S. Y. Park, B. Namkoong, D. H. Kim, K. Hur, M. W. Yoo, H. J. Lee, H. K. Yang^{✉︎ (corresponding author)}, and V. N. Kim^{✉︎ (corresponding author)}
Nucleic Acids Research (2009), 37(5):1672-1681

Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing
K. H. Yeom, Y. Lee, J. Han, M. R. Suh, and V. N. Kim^{✉︎ (corresponding author)}
Nucleic Acids Research (2006), 34(16):4622-4629

Human microRNA prediction through a probabilistic co-learning model of sequence and structure
J. W. Nam, K. R. Shin, J. Han, Y. Lee, V. N. Kim, and B. T. Zhang^{✉︎ (corresponding author)}
Nucleic Acids Research (2005), 33(11):3570-3581

STING facilitates nuclear import of herpesvirus genome during infection
Y. Hong, H. Jeong, K. Park, S. Lee, J. Y. Shim, H. Kim, Y. Song, S. Park, H. Y. Park, V. N. Kim, and K. Ahn^{✉︎ (corresponding author)}
Proceedings of the National Academy of Sciences of the U.S.A. (2021), 118(33):e2108631118

Re-evaluation of the roles of DROSHA, Exportin 5, and DICER in microRNA biogenesis
Y.-K. Kim^{✉︎ (corresponding author)}, B. Kim, and V. N. Kim^{✉︎ (corresponding author)}
Proceedings of the National Academy of Sciences of the U.S.A. (2016), 113(13):E1881-E1889

Next-generation libraries for robust RNA interference-based genome-wide screens
M. Kampmann^{✉︎ (corresponding author)}, M. A. Horlbeck, Y. Chen, J. C. Tsai, M. C. Bassik, L. A. Gilbert, J. E. Villalta, S. C. Kwon, H. Chang, V. N. Kim, and J. S. Weissman^{✉︎ (corresponding author)}
Proceedings of the National Academy of Sciences of the U.S.A. (2015), 112(26):E3384-E3391

SRSF3 recruits DROSHA to the basal junction of primary microRNAs
K. Kim¹, T. D. Nguyen¹, S. Li, and T. A. Nguyen^{✉︎ (corresponding author)}
RNA (2018), 24(7):892-898

Exogenous RNA surveillance by proton-sensing TRIM25
M. Kim, Y. Pyo, S.-I. Hyun, M. Jeong, Y. Choi, and V. N. Kim^{✉︎ (corresponding author)}
Science (2025), 388(6742):eads4539

Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation
J. Lim¹, D. Kim¹, Y. Lee¹, M. Ha, M. Lee, J. Yeo, H. Chang, J. Song, K. Ahn, and V. N. Kim^{✉︎ (corresponding author)}
Science (2018), 361(6403):701-704

Response to comment on “Multiple repressive mechanisms in the hippocampus during memory formation”
J. Cho, N.-K. Yu, V. N. Kim^{✉︎ (corresponding author)}, and B.-K. Kaang^{✉︎ (corresponding author)}
Science (2016), 353(6298):453

Multiple repressive mechanisms in the hippocampus during memory formation
J. Cho¹, N.-K. Yu¹, J.-H. Choi, S.-E. Sim, S. J. Kang, C. Kwak, S.-W. Lee, J. Kim, D. I. Choi, V. N. Kim^{✉︎ (corresponding author)}, and B.-K. Kaang^{✉︎ (corresponding author)}
Science (2015), 350(6256):82-87

Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development
D. Kang¹, J. Shin¹, Y. Cho, H. S. Kim, Y. R. Gu, H. Kim, K. T. You, M. J. Chang, C. B. Chang, S. B. Kang, J. S. Kim, V. N. Kim, and J. H. Kim^{✉︎ (corresponding author)}
Science Translational Medicine (2019), 11(486):eaar6659

Functional and molecular dissection of HCMV long non-coding RNAs
S. Lee¹, H. Kim¹, A. Hong¹, J. Song¹, S. Lee, M. Kim, S. Hwang, D. Jeong, J. Kim, A. Son, Y. Lee, V. N. Kim, J.-S. Kim, H. Chang^{✉︎ (corresponding author)}, and K. Ahn^{✉︎ (corresponding author)}
Scientific Reports (2022), 12(1):19303

High-throughput in vitro processing of human primary microRNA by the recombinant Microprocessor
K. Kim^{✉︎ (corresponding author)} and V. N. Kim^{✉︎ (corresponding author)}
STAR Protocols (2022), 3(1):101042

Bringing single-molecule spectroscopy to macromolecular protein complexes
C. Joo^{✉︎ (corresponding author)}, M. Fareh, and V. N. Kim
Trends in Biochemical Sciences (2013), 38(1):30-37

MicroRNA precursors in motion: exportin-5 mediates their nuclear export
V. N. Kim^{✉︎ (corresponding author)}
Trends in Cell Biology (2004), 14(4):156-159

Genomics of microRNA
V. N. Kim and J. W. Nam
Trends in Genetics (2006), 22(3):165-173

In vitro and in vivo assays for the activity of Drosha complex
Y. Lee and V. N. Kim
Methods in Enzymology (2007), 427:87-106

Drosha in primary microRNA processing
Y. Lee, J. Han, K. H. Yeom, H. Jin, and V. N. Kim
Cold Spring Harbor Symposia on Quantitative Biology (2006), 71:51-57

Preparation and analysis of Drosha
Y. Lee and V. N. Kim
Methods in Molecular Biology (2005), 309:17-28